抗人CD270(HVEM,TR2)荧光标记APC抗体试剂盒DHL/UPS快递到加纳

抗人CD270(HVEM,TR2)荧光标记APC抗体试剂盒DHL/UPS快递到加纳

anti-human CD270 (HVEM, TR2) Antibody-APC详细如下:

Description :The 122 antibody recognizes human HVEM also known as herpesvirus entry mediator A, tumornecrosis factor receptor superfamily, member 14, TNFRSF14, and tumor necrosis factorreceptor like 2. HVEM, a member of the TNFR superfamily, is a type I transmembrane proteincontaining 2 TNF receptor domains with a predicted molecular weight of approximately 30 kD.HVEM is widely expressed in blood vessels, brain, heart, kidney, liver, lung, prostate, spleen,thymus and other organs. Resting T cells and na?ve and memory B cells express high levels ofHVEM as well. In humans, HVEM is not expressed in germinal center B cells. Immature dendriticcells express high levels of HVEM that is downregulated upon maturation. HVEM plays animportant role in herpes simplex virus pathogenesis by enhancing entry into cells. Signalingthrough HVEM activates JNK1, NF-κB and AP-1 to control gene expression in response toinfection or cellular stress and activate the immune response. HVEM binds to LIGHT and hasalso been shown to associate with several other proteins including TRAF1, TRAF2, TRAF3,TRAF5, B and T lymphocyte associated protein (BTLA), and estrogen receptor alpha.

Verified Reactivity :Human

Reported Reactivity :African Green, Baboon, Cynomolgus, Rhesus

Antibody Type :Monoclonal

Host Species :Mouse

Immunogen :Recombinant human HVEM protein

Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation :The antibody was purified by affinity chromatography and conjugated with APC under optimalconditions.

Concentration :Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)

Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.

Application :FC - tested

Recommended Usage :Each lot of this antibody is control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 μl per million cells in100 μl staining volume or 5 μl per 100 μl of whole blood.

Excitation Laser :Red Laser (633 nm)

参考文献:

1. Cheung TC, et al. 2010. J. Immunol. 185:1949. PubMed

2. Hobo W, et al. 2012. J Immunol. 189:39. PubMed.

产品引用:

1. Xu X, et al. 2020. J Cell Biol. 219:00:00. PubMed

2. Manresa MC, et al. 2020. Gastroenterology. 159:1778. PubMed

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抗人CD270(HVEM,TR2)荧光标记APC抗体试剂盒DHL/UPS快递到加纳